Brent Busby graduated from the Atlanta Institute of Music in 1994 with a degree in Music Theory. He then attended Full Sail University from 1996 to 1998, where he graduated with a Bachelor of Arts degree in Audio Engineering.
He joined Turner Broadcasting in 2005 spreading his time over both Cartoon Network and Adult Swim. He also joined the Toonami staff working as a sound editor/composer.
In 2008 with the cancellation of Toonami, the Toonami staff integrated into Cartoon Network and Adult Swim, where they still work today. After the 2012 April Fools Joke on Adult Swim, which saw Toonami revived for one night, Toonami was officially brought back, with the Toonami staff working on it for free, in their spare time.